What is hypothyroidism PDF?

Hypothyroidism is a condition characterized by abnormally low thyroid hormone production. There are many disorders that result in hypothyroidism. These disorders may directly or indirectly involve the thyroid gland.

What is the most common cause of subclinical hypothyroidism?

The most common cause of subclinical hypothyroidism is a condition known as Hashimoto thyroiditis, a disease that involves inflammation and damage to the thyroid gland because of antibodies against a person’s own thyroid gland.

What is subclinical hypothyroidism range?

Most labs say that a normal serum TSH level is somewhere between 0.4 to 4.0 mIU/L, and that a TSH level of 10 mIU/L or higher is indicative of hypothyroidism. A TSH level of 4.5 to 10 mIU/L is considered indicative of subclinical hypothyroidism.

What is the treatment of subclinical hypothyroidism?

TREATMENT. Recommended treatment for all patients with overt hypothyroidism is levothyroxine, a synthetic thyroid hormone. The starting dose for younger patients without CVD is 1.6 mcg/kg/day. Lower starting doses of 12.5 to 25 mcg/day with gradual dose increases are recommended for older adults and patients with CVD.

What is the classification of hypothyroidism?

Hypothyroidism can be classified as primary (due to thyroid hormone deficiency), secondary (due to TSH deficiency), tertiary (due to thyrotropin-releasing hormone deficiency), and peripheral (extra-thyroidal; panel).

What is the treatment for subclinical hypothyroidism?

Levothyroxine, in a dosage that maintains serum TSH levels within the normal range, is the preferred therapy in these patients. Hypothyroidism is quite common in older persons.

What is treatment for subclinical hypothyroidism?

Patients with subclinical hypothyroidism, because of the minimal extent of the thyroid hormone deficiency, may be controlled with total daily dosages of levothyroxine as low as 25 to 50 μg.

What causes subclinical hyperthyroidism?

Common causes of endogenous subclinical hyperthyroidism include Graves disease, autonomous functioning thyroid adenoma, and multinodular toxic goiter. Transient TSH suppression may occur during subacute, painless (silent), or postpartum thyroiditis. Iodine-deficient areas have a higher prevalence of thyroid autonomy.

What level of TSH needs treatment?

If your TSH level is higher than 10 mIU/L, you should start treatment, because you will very likely develop symptoms of an underactive thyroid, even if you don’t have them now.

What is the difference between hypothyroidism and subclinical hypothyroidism?

Hypothyroidism is characterized by increased thyrotropin (TSH) levels and reduced free thyroid hormone fractions while, subclinical hypothyroidism (sHT) by elevated serum TSH in the face of normal thyroid hormones.

What are the three types of hypothyroidism?

In hypothyroidism, your thyroid doesn’t produce enough of these hormones. This is also known as an underactive thyroid. There are three types of hypothyroidism: primary, secondary, and tertiary.

How is subclinical hypothyroidism treated?

Are there symptoms with subclinical hypothyroidism?

About 70% of patients with subclinical hypothyroidism have no symptoms. Tiredness was more common in subclinical hypothyroid patients with TSH levels lower than 10 mIU/L compared with euthyroid controls in 1 study, but other studies have been unable to replicate this finding.

When to treat subclinical hypothyroidism?

Aim to resolve symptoms and signs of hypothyroidism.

  • Aim to maintain serum TSH and FT4 levels to within or close to the normal reference range.
  • If symptoms persist,consider adjusting the dose of LT4 further to achieve optimal wellbeing,taking care to avoid over-treatment.
  • Should you treat subclinical hypothyroidism?


  • Depression,anxiety and moodiness
  • Increased sensitivity to cold
  • Constipation
  • Dry skin
  • Weight gain
  • Puffy face
  • Muscle weakness,aches,tenderness and stiffness
  • Heavier than normal or irregular menstrual periods
  • Thinning hair
  • Why subclinical hypothyroidism may increase heart disease risk?

    “Hypothyroidism has known effects on multiple cardiovascular pathways, including adverse effects on systolic and diastolic function, endothelial function, and lipid levels, and our study suggests that if someone has higher underlying cardiovascular risk, they may be more vulnerable to the effects of mild hypothyroidism,” says Connie Rhee, MD, of Brigham and Women’s Hospital in Boston, and lead author of the study.

    What is the best treatment for hypothyroidism?

    Hypothyroidism is when the thyroid gland produces a reduced amount of thyroid hormone. The best treatment for hypothyroidism is to take thyroid hormone replacement medication. The thyroid produces hormones that regulate many different functions in the body, including your heart rate, metabolism, and body temperature.