What is the chemical structure of TSH?
TSH is a peptide hormone produced by the anterior pituitary. It consists of two chains: an alpha chain and a beta chain. It has a molecular mass of approximately 28,000 Da. The composition is very similar to other glycoprotein hormones made by the anterior pituitary.
What is TSH also known as?
TSH stands for thyroid stimulating hormone. A TSH test is a blood test that measures this hormone. The thyroid is a small, butterfly-shaped gland located near your throat. Your thyroid makes hormones that regulate the way your body uses energy.
How is TSH produced?
Thyroid stimulating hormone is produced and released into the bloodstream by the pituitary gland. It controls production of the thyroid hormones, thyroxine and triiodothyronine, by the thyroid gland by binding to receptors located on cells in the thyroid gland.
What is the secret of TSH?
The most important controller of TSH secretion is thyroid-releasing hormone. Thyroid-releasing hormone is secreted by hypothalamic neurons into hypothalamic-hypophyseal portal blood, finds its receptors on thyrotrophs in the anterior pituitary and stimulates secretion of TSH.
What type of chemical is thyroxine?
Thyroxine is an iodothyronine compound having iodo substituents at the 3-, 3′-, 5- and 5′-positions. It has a role as a mitogen. It is an iodothyronine, a 2-halophenol, an iodophenol, a tyrosine derivative and a non-proteinogenic alpha-amino acid. It is a tautomer of a thyroxine zwitterion.
Is TSH hormone A protein?
TSH, similar to other glycoprotein hormones, is a glycosylated protein.
What is the function of TSH in your body?
Thyroid stimulating hormone (TSH), also known as thyrotropin or thyrotrophin, is a hormone that controls the way other hormones function. Basically, it stimulates the production of two main hormones, T4 (thyroxine) and T3 (triiodothyronine), hence its name: thyroid stimulating hormone.
What hormone affects TSH?
Your hypothalamus releases thyrotropin-releasing hormone (TRH), which triggers your pituitary gland to release thyroid-stimulating hormone (TSH), which stimulates your thyroid to release T3 and T4.
What hormone increases TSH?
Hypothalamus releases thyrotropin-releasing hormone (TRH) that stimulates the secretion of TSH in the pituitary gland.
What is thyroxine formula?
DL-Thyroxine | C15H11I4NO4 – PubChem.
How many amino acids are in TSH?
118 amino acids
The TSHB gene of the TSH-β subunit was first cloned in 1988 (37) and is located on chromosome 1 (1p13). It encodes a polypeptide chain of 118 amino acids in length without the signal peptide (38).
What is the full form of T3?
This test measures the level of triiodothyronine (T3) in your blood. T3 is one of two major hormones made by your thyroid, a small, butterfly-shaped gland located near the throat. The other hormone is called thyroxine (T4.) T3 and T4 work together to regulate how your body uses energy.
What is TSH and how is It measured?
Measuring the TSH levels is considered the best way to diagnose the thyroid disorders. It is also called Thyrotropin. The history of TSH researches began with the discovery of thyroid-stimulating activity in the pituitary gland.
What is the chemical structure of TSH (Thyroid stimulating hormone)?
Chemical structure of TSH. When we talk about the chemical structure of the Thyroid-Stimulating Hormone, we should know that it consists of two subunits, the alpha and the beta subunit. The alpha subunit is chemically identical to human chorionic Gonadotropin hormone, luteinizing hormone and follicle-stimulating hormone.
What is the molecular formula of thyroid hormones?
Thyroid hormones PubChem CID 53462828 Structure Find Similar Structures Molecular Formula C30H23I7N2O8 Synonyms Thyroid hormones SCHEMBL9755105 EINECS 2 Molecular Weight 1427.8
What is the α and β chain of TSH?
The α chain has a 92-amino acid sequence. The β ( beta) subunit ( TSHB) is unique to TSH, and therefore determines its receptor specificity. The β chain has a 118-amino acid sequence.