What are the main difference between Hodgkin HL and non-Hodgkin lymphomas NHL at the cellular level?
Lymphoma is a group of cancers that develop in immune cells called lymphocytes. The two main categories of lymphoma are Hodgkin’s lymphoma and non-Hodgkin’s lymphoma. The main difference between them is the atypical cells called Reed-Sternberg cells. These cells are only seen in Hodgkin’s lymphoma.
How does NHL affect the lymphatic system?
In non-Hodgkin lymphoma, the affected lymphocytes start to multiply in an abnormal way and begin to collect in certain parts of the lymphatic system, such as the lymph nodes (glands). The affected lymphocytes lose their infection-fighting properties, making you more vulnerable to infection.
Can you have both Hodgkin’s and non-Hodgkin’s lymphoma?
The occurrence of HD and NHL in an individual is unusual. Tumour biological features common to both HD and NHL may indicate a similar cellular origin, regardless of the time interval between the diagnoses, and may contribute to the understanding of the pathogenesis of lymphoma.
How do we differentiate lymphocytic leukemias from lymphomas?
“The simplest way to think about it is that lymphomas are solid tumors made up of blood cells. This kind of cancer usually causes enlarged lymph nodes or solid masses. Leukemia, on the other hand, is seen in the bloodstream – it’s a liquid kind of cancer and it flows and is pumped around with the blood.”
Which form of lymphoma is worse?
The type of chemotherapy you receive will depend on how aggressive the cancer is. “T-cell non-Hodgkin lymphomas tend to be more aggressive,” Strati says. “Whereas B-cell non-Hodgkin lymphomas may be more slow-growing.”
What causes NHL?
Non-Hodgkin lymphoma is caused by a change (mutation) in the DNA of a type of white blood cell called lymphocytes, although the exact reason why this happens isn’t known. DNA gives cells a basic set of instructions, such as when to grow and reproduce.
Can you have Hodgkin’s and non-Hodgkin’s lymphoma at the same time?
Are all leukemias and lymphomas are malignant?
A type of Cancer that begins with a malignant change in a lymphocyte, lymph node cell or lymphatic tissue of the marrow. Both Lymphocytic Leukemia and Lymphoma are the result of a malignant transformation of a cell destined to be a lymphocyte.
What is the difference between lymphoma and myeloma?
Multiple myeloma (MM) and lymphoma are both cancers that affect cells in a person’s blood. MM is a cancer of plasma cells, while lymphoma is a cancer of lymphocytes. Both plasma cells and lymphocytes are types of white blood cell.