When is HAE day?

May 16
hae day đŸ™‚ May 16: Hereditary Angioedema Awareness.

What is Hae disease?

Hereditary angioedema is a rare inherited disorder characterized by recurrent episodes of the accumulation of fluids outside of the blood vessels, blocking the normal flow of blood or lymphatic fluid and causing rapid swelling of tissues in the hands, feet, limbs, face, intestinal tract, or airway.

What HAE looks like?

HAE Attacks That Affect The Face Swelling of the face is one of the most obvious signs of an HAE attack. If your eyes swell up, it might be hard to see. Inflamed lips could make talking, eating, or drinking difficult. In some cases, your entire face may appear disfigured.

How is HAE treated?

BERINERT® is a plasma-derived C1 Esterase Inhibitor (Human) indicated for the treatment of HAE attacks in adult and pediatric patients. Berinert is delivered intravenously and is approved for self-administration.

How many people HAE in the world?

Epidemiology. HAE is a rare disease that affects about 1 in 50,000 people in the entire world.

Who treats HAE?

Your healthcare team should feature a doctor who has treated HAE, usually an allergist-immunologist. Other specialists who may be on your HAE care team include dermatologists, genetic counselors, OB-GYNs, and gastroenterologists.

Is HAE a disability?

Principal findings: HAE may result in physical and/or psychological disability because of the lack of effective treatments and the unpredictability of symptom severity.

Is HAE life-threatening?

Hereditary angioedema (HAE) is a rare but potentially life-threatening disease affecting approximately 1 in 67,000 individuals, with no identified differences in prevalence due to sex or ethnicity.

How do you treat HAE?

In HAE types I and II, the treatment of choice in acute attacks consists of replacement with commercially available C1 inhibitor (C1-INH) concentrates or kallikrein inhibitor or, if those are unavailable, fresh-frozen plasma. In HAE with normal C1 inhibitor levels, infusion of C1-INH has proven to be ineffective.

How many HAE patients are in Europe?

It occurs in approximately 1:30,000–80,000 individuals and affects less than 8,000 individuals in the United States (USA), 15,000 in Europe, and 200,000 worldwide (3, 4) Disease-specific therapy for HAE, although available in other countries since 1979 (5), only recently became available in the USA.

Does hereditary angioedema ever go away?

These types are also characterized by abnormal complement protein levels. Inheritance is autosomal dominant, but not all people with a SERPING1 genetic change will develop symptoms of HAE. Attacks generally continue throughout life, but the frequency of attacks can be significantly reduced with therapy.

Can hereditary angioedema start later in life?

Background. Hereditary angioedema with C1 inhibitor deficiency (C1-INH-HAE) is characterized by recurrent swelling in subcutaneous or submucosal tissues. Symptoms often begin by age 5–11 years and worsen during puberty, but attacks can occur at any age and recur throughout life.

Is there a cure for HAE?

There is no cure for HAE, but there are things you can do to help manage your condition. Your doctor can help you understand the 2 main treatment types, preventive and on-demand, and how they might play a role in your management plan.

Are you born with hereditary angioedema?

Hereditary angioedema is genetic (a trait inherited from a parent). The condition is present at birth, but symptoms usually start when you’re a child or teenager. Acquired angioedema can develop after you get certain cancers or autoimmune diseases.

What triggers HAE?

Triggers of an HAE attack Emotional stress. Injury. Infection. Dental procedures or tonsillectomy.

Is HAE an autoimmune disease?

HAE may be associated with autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis, autoimmune thyroiditis and glomerulonephritis2–5). Idiopathic hypoparathyroidism may be developed by autoimmune mechanism as a part of polyglandular autoimmune syndrome or as an isolated hypoparathyroidism6–7).

What kind of doctor treats HAE?

An allergist-immunologist is a doctor who diagnoses and treats conditions of the immune system, including asthma, allergies, and HAE. C1-INH, the protein that is lacking in HAE, is part of your immune system. An allergist-immunologist may have diagnosed you with HAE. This doctor will plan and oversee your treatment.

Is HAE life threatening?

Is angioedema considered a disability?

As noted above, the veteran’s service-connected idiopathic anaphylaxis with recurrent angioedema is currently rated as 40 percent disabling pursuant to 38 C.F.R. § 4.104, Diagnostic Code 7118 for angioneurotic edema. This is the maximum rating under that diagnostic code.